Rolls Royce UTC, University Of Virginia
- Interstate 64 runs directly through the region, easily connecting Central Virginia to destinations to the east and west.
- Interstates 64 and 66 connect Central Virginia to Interstates 81 and 95 for access to north/south destinations.
- U.S. Route 29 runs through most of the region, connecting to destinations from Florida to the Greater Washington, D.C., area.
- Freight rail service is provided by CSX Transportation, Norfolk Southern, Buckingham Branch Railroad.
- Passenger rail service is provided by Amtrak, providing multiple daily trains to and from Washington, D.C., New York, and beyond.
- The Virginia Inland Port at Front Royal is 30 miles north of Central Virginia, and The Port of Virginia in Hampton Roads is 90 miles east.
- The Charlottesville Albemarle Regional Airport (CHO) provides direct, daily flights to Atlanta, Charlotte, Chicago, New York City, Philadelphia, and Washington, D.C.